منابع مشابه
Computed Tomography of Lethal Midline Granuloma
In order to clarify the CT findings oflethal midline granuloma (LMG) diagnosed clinically or histopathologically , the authors retrospectively analyzed 12 patients who were seen at Kyungpook National University Hospital from February 1985 to August 1989. CT showed nasal mucosal thickening and/or soft tissue mass (9 cases) , spreading of the lesions along the facial subcutaneous fat plane (8 cas...
متن کاملPathology of 'non-healing (midline) granuloma'.
In a histological study of biopsy and postmortem material from 30 cases of nasal disease in which a clinical diagnosis of 'midline granuloma' or Wegener's granuloma had been given, we selected 10 cases on the basis of the presence of widespread coagulative necrosis and atypical cells. Evidence is provided that such changes represent a malignant neoplasm of histiocytic lymphoma type. Local invas...
متن کاملHypomorphic Rag mutations can cause destructive midline granulomatous disease.
Destructive midline granulomatous disease characterized by necrotizing granulomas of the head and neck is most commonly caused by Wegener granulomatosis, natural killer/T-cell lymphomas, cocaine abuse, or infections. An adolescent patient with myasthenia gravis treated with thymectomy subsequently developed extensive granulomatous destruction of midface structures, palate, nasal septum, airways...
متن کاملBiopsy findings in malignant histiocytosis presenting as lethal midline granuloma.
Nasal biopsy findings in malignant histiocytosis presenting clinically as lethal midline granuloma are characterised by necrosis and infiltration of atypical histiocytic cells with a diffuse positive reaction for non-specific esterase. This cellular character was common to midline malignant reticulosis, and midline malignant reticulosis and malignant histiocytosis are thought to be the same dis...
متن کاملDifferentiation of Cocaine-Induced Midline Destructive Lesions from ANCA-Associated Vasculitis
Introduction: Cocaine-induced midline destructive lesions (CIMDL) are complications of regular nasal cocaine inhalation. CIMDL can mimic systemic diseases with positive anti-neutrophil cytoplasmic antibodies (ANCA), such as granulomatosis with polyangiitis (GPA). Case Report: In this article, we describe the case of a young woman who presented with nasal perforation induced by cocaine, al...
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ژورنال
عنوان ژورنال: The Laryngoscope
سال: 1987
ISSN: 0023-852X
DOI: 10.1288/00005537-198709000-00010